ICEC mourns the loss of Rodney R. Million, MD., a pioneer in radiation oncology

ICEC mourns the loss of Dr. Rodney R. Million, a pioneer in radiation oncology and a true innovator combining technology with research to improve the quality of cancer care in the US and abroad.  He was a champion of treating patients undergoing cancer treatment with dignity regardless of their ability to pay. He understood the value of clinical research to reduce mortality and improve the quality of life for those with cancer.

Rodney R. Million Fund for Innovation in Clinical Care

In 2018, in honor of Rodney’s transformational and innovative career, the Million family established the Rodney R. Million Fund for Innovation in Clinical Care. Recipients of the award provide a new skill set to the oncology team in cancer clinics and other areas within low- and middle-income countries worldwide.

Working with and supporting these leaders of the next generation, the Million fund, through ICEC, will help sustain careers and other related activities in global health and service to these struggling countries and other areas.  Read more about Dr. Million and the Rodney R. Million Fund for Innovation in Clinical Care.

Rodney R. Million, MD., Obituary. The Gainesville Sun Feb. 2 to Feb. 3, 2021

Rod Million was born in Idaville, Indiana, and raised in Bloomington, where he graduated with a B.S in Anatomy and Physiology from Indiana University in 1950 and continued his post-graduate education, obtaining an MD in 1954. He served as a flight surgeon in the U.S. Air force from 1955-1958 in Morocco. After training in Therapeutic Radiology at MD Anderson Cancer Hospital in Houston, Texas, he took a position at the University of Florida, where he served as Chair and Professor from 1964 to 1992. He wrote numerous papers and books on his specialty, cancers of the head and neck. He was president of ASTRO (American Society of Therapeutic Radiology Radiation Oncology) in 1990 and honored with the Presidential Gold Medal in 1995. He was on the Board of Trustees of the American Board of Radiology, a founding member of the Fletcher Society, and editor for the International Journal of Radiation Oncology Biology of Physics. He served many public appointments, including the American Cancer Society and National Cancer Institute.

Rod was an avid fisherman and always up for a quick strike to locations across Florida with his friends or sons. Rod enjoyed painting, growing roses and building exquisite wooden canoes and surfboards at his Lake Santa Fe house. He is survived by his wife Marge, sons Jeff, Brad and Steve (Stephanie) and daughter Lynn, six grandchildren and one great-grandchild. The family will have a private service.

In 2018 the Million family established the Dr. Rodney R. Million Fund for Innovation and Clinical Care through International Cancer Expert Core (ICEC), supporting medical students and doctors in the fight against cancer in low-income countries. In lieu of flowers, donations in his honor can be made to the ICEC at Rodney R. Million fund for Innovation in Clinical Care.

Research-Driven Radiation Oncology: A Narrative on the Ongoing Legacy of Henry S. Kaplan

In this rapidly evolving time of precision medicine and scientifically based cancer care, how radiation oncology became a strong research-based scientific discipline in the United States after its separation from diagnostic radiology might be lost. The importance of generational mentorship, “family trees,” and interpersonal relationships can be difficult or impossible to trace absent personal narrative recollections of those involved. Henry S. Kaplan is a central figure and the focal point for 3 generations of research-based academic department chairs. This report establishes a first draft of a living record of the radiation oncology history of the Kaplan legacy to serve as an example of how knowledge networks grow and flourish and as an impetus for others to trace the legacy of other radiation oncology academic “trees.” Read the full article…
Published by Elsevier Inc.

 

Achieving flexible competence: bridging the investment dichotomy between infectious diseases and cancer

Today’s global health challenges in underserved communities include the growing burden of cancer and other non-communicable diseases (NCDs); infectious diseases (IDs) with epidemic and pandemic potential such as COVID-19; and health effects from catastrophic ‘all hazards’ disasters including natural, industrial or terrorist incidents. Healthcare disparities in low-income and middle-income countries and in some rural areas in developed countries make it a challenge to mitigate these health, socioeconomic and political consequences on our globalised society. As with IDs, cancer requires rapid intervention and its effective medical management and prevention encompasses the other major NCDs. Furthermore, the technology and clinical capability for cancer care enables management of NCDs and IDs. Global health initiatives that call for action to address IDs and cancer often focus on each problem separately, or consider cancer care only a downstream investment to primary care, missing opportunities to leverage investments that could support broader capacity-building. From our experience in health disparities, disaster preparedness, government policy and healthcare systems we have initiated an approach we call flex-competence which emphasises a systems approach from the outset of program building that integrates investment among IDs, cancer, NCDs and disaster preparedness to improve overall healthcare for the local community. This approach builds on trusted partnerships, multi-level strategies and a healthcare infrastructure providing surge capacities to more rapidly respond to and manage a wide range of changing public health threats. Read the article…

 

Article: Coleman CN, Mansoura MK, Marinissen MJ, et al. Achieving flexible competence: bridging the investment dichotomy between infectious diseases and cancer. BMJ Global Health 2020;5:e003252. doi:10.1136/ bmjgh-2020-003252

Capturing Acquired Wisdom, Enabling Healthful Aging, and Building Multinational Partnerships Through Senior Global Health Mentorship

Capturing the acquired wisdom and experience of mentors in global health offers a capstone for their careers and provides a purposeful healthspan for these professionals to continue to be engaged in meaningful work while leveraging their expertise to solve challenging health care problems. This article addresses such opportunities available for individuals in the latter part of their careers including postretirement done either as a continuation of their role as career-long mentors or as a new challenge to be met with their lifelong experience. The expanding and branching tree of mentors to mentees enables a career path in global health and geometric growth to fill in the current enormous capacity gap.  Read the full article…

 

The number of people per radiotherapy machine per African country

Designing new radiotherapy technologies to treat cancer in low and middle-income countries

June 11, 2020

Innovative Technologies towards building Affordable and equitable global Radiotherapy capacity (ITAR)

A new project, “Innovative Technologies towards building Affordable and equitable global Radiotherapy capacity” (ITAR), supported by the Science and Technology Facilities Council (STFC), aims to design and develop new radiotherapy technologies to give more cancer patients in Sub-Saharan Africa access to treatment and to save lives. The project will contribute to the development of novel radiotherapy machines, specifically designed to meet the needs of African hospitals. The challenge brings together an international team of accelerator physicists and engineers, medical physicists, radiobiologists, radiation oncologists, radiologists, IT experts, and health system researchers.

The state of cancer care

The number of people per radiotherapy machine per African country

The annual global incidence of cancer is projected to rise to 27.5 million cases by 2040, leading to more than 13 million deaths. Up to 70 percent of these will occur in low and middle-income countries (LMICs). Radiotherapy is an essential component of cancer care being a very effective means of curing the disease, as well as palliative treatment, and where available, is used to treat more than half of patients.

Many low and middle-income countries in Africa have acute shortages of radiotherapy machines. In the lowest-income countries, only four percent of cancer patients that need radiotherapy treatment are able to be treated. There are currently only 385 radiotherapy machines in the region, and 60 percent of those are located in just three countries – South Africa, Egypt and Morocco.

A report by the Lancet Oncology Commission – Global Task Force on Radiotherapy for Cancer Control (GTFRCC) of the Union for International Cancer Control (UICC) recently estimated that by 2035 at least 5,000 additional megavolt-class treatment machines would be needed to meet radiotherapy demands in low-and middle-income African countries.

A collaborative effort

The ITAR project, a critical part of a larger international project that includes the International Cancer Expert Corps (ICEC), CERN, STFC (Daresbury Laboratory), and Lancaster University, is led by Lancaster University and Oxford University and will bring together partners from the Cockcroft Institute, STFC’s Accelerator Science and Technology Centre (ASTeC), John Adams Institute, Swansea University, King’s College London, ICEC and CERN.

In ITAR’s first phase, the project will define the persistent shortfalls in basic infrastructure, equipment and specialist workforce which remain barriers to effective radiotherapy delivery, and develop novel solutions leading to a detailed specification and conceptual design. The project will then progress to a prototype development phase at STFC’s Daresbury Laboratory.

Professor Manjit Dosanjh, from CERN and Oxford University, and member of the ICEC Board of Directors, and who leads the overall international project, said: “I am really excited that the idea, first presented by Dr Norman Coleman of the International Cancer Expert Corps at the 2014 ICTR-PHE meeting held in Geneva, continues to flourish. Having Lancaster and Oxford Universities, along with Daresbury Laboratory and others working on this with STFC’s critical support and ICEC’s expertise, is a significant step in addressing the need for a novel medical linear particle accelerator to generate the radiation for LMICs and other challenging environments.”

Local stakeholder participation is vital to the project’s success

Dr. Taofeeq Ige (National Hospital Abuja, Nigeria) in front of one of the hospitals radiotherapy LINACs

Dr. Taofeeq Ige (National Hospital Abuja, Nigeria) in front of one of the hospital’s radiotherapy LINACs.

A critical aspect of the project’s challenge cluster is the involvement of the international partners. Dr. Taofeeq Ige and Dr. Simeon Aruah, of the National Hospital Abuja, Nigeria, and Dr. Surbhi Grover, of the Botswana-UPENN Partnership and Princess Marina Hospital, are key partners working in African hospitals. They will gather information from a network of other hospitals in Botswana, Ghana, Kenya, Nigeria, South Africa, Tanzania, Zambia and Zimbabwe and play a key role in the definition of the specification for the new machines.

In addition, ICEC provides a network of international oncologists, medical physicists, and engineers working in radiotherapy systems. They are already providing training and mentorship in lower- and middle-income countries and will continue with their assistance in the development of the radiotherapy system in this project.

Professor Graeme Burt, of Lancaster University and the Cockcroft Institute, and who is leading the phase 1 project said: “Current radiotherapy machines are optimised for use in western countries. The ITAR project aims to design specifically for use in Africa making it far more tolerant to the local environment, which will greatly increase the capacity for more lives to be saved.”

Professor Deepa Angal-Kalinin, of STFC and the Cockcroft Institute, University of Manchester, and who is leading the accelerator design said: “I am keen to apply the knowledge and expertise at Daresbury Laboratory to develop a novel medical linac design in this phase of the project which will prepare us to build a prototype to test our novel ideas.”

Media queries should be sent to:
nina.wendling@iceccancer.org or graeme.burt@cockcroft.ac.uk

Emphasizing the critical importance of EXPERTISE

A Broad Impact for Global Oncology
JAMA Oncology, August 8, 2019. Co-authors from International Cancer Expert Corps

Emphasizing the critical importance of EXPERTISE, the article, “A Broad Impact for Global Oncology” available at the bottom of this post and online at https://jamanetwork.com/journals/jamaoncology/fullarticle/2747881, emphasizes the breadth of opportunities for global oncology. The critical need for mentorship is a driving force of ICEC with the creation of a career path being essential.  The breadth of expertise required- noted on the ICEC website- creates an opportunity for many participants in all stages of their careers.

Figure 1 from the paper includes all that can be accomplished, requiring global partnerships, innovative thinking and built up Expertise.

The paper concludes: “The size and complexity of the problems present a grand challenge worthy of the best minds and transformational approaches, often requiring partnerships that have the potential for common projects even among countries and neighbors who have political conflicts. How could one not want to eradicate cancer and its deleterious impact? The Figure provides the components and benefits of a systems approach that supports leading-edge science and technology but, critically, pays attention to those populations historically and currently left behind in the trailing-edge turbulence of inequality. In this way, creativity, innovation, altruism, and commitment can bring rewarding results.”

The critical need for mentorship is a driving force of ICEC with the creation of a career path being essential.  The breadth of expertise required- noted on the ICEC website- creates an opportunity for many participants in all stages of their careers.

A Broad Impact for Global Oncology

A Broad Impact for Global Oncology

Global oncology demands attention, with approximately 9 million people dying from cancer annually. It provides an extraordinary opportunity to address the urgent need for cancer care and be a catalyst for solutions to address critical societal issues including the disruptive forces in and among countries involving the health of individuals and the planet, relationships among cultures, the digital revolution, inequality, and the sociopolitical conflict of globalism vs isolationism.  Read the article published online in JAMA Oncology

Job opportunity with the IAEA

Great opportunity to work at the IAEA! A 2-year global health position is for a Junior professional (JPO) in the Division of Human Health (NAHU) supported through the US government.   Click here for job listing. Apply through Argonne National labs.

April 30th deadline!